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Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Reason:Studies have shown that sildenafil citrate and nitrate react with each other. Besides effectively treating erectile dysfunction, sildenafil citrate (Solvetra 40 mg) also holds the potential to treat other medical conditions such as muscular dystrophy, cardiovascular disorders and cancer (in combination with other drugs). The study appearing in EMBO Molecular Medicine, demonstrates for the first time that 4-aminopyridine (4AP), a drug currently used to treat patients with the chronic nerve disease, multiple sclerosis, has the unexpected property of promoting recovery from acute nerve damage. The industry is likely to experience a decline in revenue mainly due to the expiration of patents of key drug molecules around 2019. The main line of drugs for erectile dysfunction treatment includes Vitaros, Zydena, Stendra, Levitra, Cialis, and Viagra. 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